Glaukos Avedro
Cross-linking


The only therapy of
keratoconus approved
by the FDA

(United States Food and Drug Administration)

The cross-linking procedure patented by
Glaukos Avedro is the first and only therapy approved by the
United States Food and Drug Administration
which strengthens the cornea and slows down the progression of keratoconus

Keratoconus is a condition in which the normal spherical shape of the cornea becomes thinner and progressively weakens causing a cone-shaped deformation.

This deformation can cause a severe deterioration of vision and in the most advanced cases the progressive thinning of the cornea can make a cornea transplant necessary.
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Keratoconus is a rare disease, typically diagnosed in the early twenties, and can progress for ten to twenty years before slowing down or leveling off. 

Keratoconus is always bilateral but the two eyes can be affected differently.

The main symptoms are:
  • Blurry vision
  • Distorted vision
  • Increased sensitivity to light
Keratoconus therapies correct distorted vision caused by corneal deformation and strengthen or repair its structure.

Currently the options are:
  • Glasses
  • Hard contact lenses
  • Corneal implants
  • Corneal cross-linking
  • Corneal transplant

Keratoconus in the absence of adequate treatment
can cause severe vision loss
and may require multiple corneal transplants,
seriously threatening the quality of life of patients

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Corneal cross-linking is a minimally invasive procedure that combines the use of eye drops with Vitamin B2 and an ultraviolet system to stop the progression of keratoconus.
  • It creates new cross-links between the collagen fibers that make up the cornea
  • The fibrils shorten and become thicker
  • The cornea becomes stiffer and firmer
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The ophthalmologist will apply some eye drops which will be left to rest for about 10 minutes.

The eye will then be exposed to ultraviolet rays for 10 minutes and the treatment is complete.
  • Avoid rubbing your eyes for five days after the procedure.
  • You may notice discomfort in the light and a foreign body sensation, using sunglasses will help you feel better.
  • You may wear protective contact lenses
Following treatment with Glaukos Avedro KXL it is very important that you follow your doctor's instructions and that you show up on time for checkups to avoid unpleasant complications.
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In April 2016, the US FDA approved Photrexa® Viscous, Photrexa® and the KXL® System for corneal cross-linking, a minimally invasive procedure that combines the use of eye drops with Vitamin B2 and ultra-violet light (UV)

Glaukos Avedro is currently the only therapy for keratoconus to have obtained this important certification

Glaukos Avedro cross-linking is available at

Aci Castello - Doctors Zagari

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Bologna - Dr. Muraca Perrone

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Bologna-Sant'Orsola - Prof. Luigi Fontana

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Brescia - Eyecare eye centre

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Cagliari - Dr. Paolo Tronci

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Campobasso - Dr. Paolo Polisena

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Castel San Pietro Terme - Dr. Rocco De Fazio

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Catania - Dr. Francesco Famà

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Catanzaro - Dr. Miguel Rechichi

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Conegliano Veneto - Dr. Giovanni Prosdocimo

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Correggio - Dr Marco Vecchi

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Cosenza - Dr. Miguel Rechichi

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Cuneo - Dr. Guido Caramello

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Domodossola - Dr. Romolo Protti

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Genoa - Health Ultralaser

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Lugano - Dr. Lorenzo Artaria

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Mascalucia - Dr. Salvatore Lo Grasso

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Mestre - Dr. Dario Surace

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Milan - Dr. Francesco Carones

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Milan - Quattroelle eye studio

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Modena - Dr. Paola Benedetti

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Modena - Dr. Gianmaria Cavallini

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Modena - Dr. Federico Nizzola

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Morrovalle - Dr. Vincenzo Ramovecchi

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Naples - Day Surgery Center

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Naples - Dr. Alfredo Venosa

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Naples - VanvitelliI University Hospital

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Padua - Dr Paolucci Pierpaolo

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Parma - Dr. Claudio Macaluso

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Pavia - Dr. Roberto Ceccuzzi

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Piacenza - Dr. Luigi Lodigiani

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Pisa - Dr. Marco Fantozzi

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Reggio Calabria - Dr. Demetrio Spinelli

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Rome - Prof. Aldo Caporossi

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Rome - Gemelli Hospital

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Rome - Dr. Luca Gualdi

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Rovigo - Dr. Luigi Caretti

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San Benedetto del Tronto - Dr. Luca Cesari

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San Severino Marche - Dr. Vincenzo Ramovecchi

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Sassari - Dr. Paola Piccinini

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Selargius - Dr. Miguel Rechichi

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Siena - Prof. Cosimo Mazzotta

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Siena - Prof. Aldo Caporossi

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KXL is manufactured by the leading American cross-linking company Glaukos Avedro.

​https://glaukos.com/

Page intended for healthcare professionals.
In compliance with the provisions provided by the Ministry of Health regarding health advertising relating to medical devices, in vitro diagnostic medical devices and medical-surgical aids, we inform you that the contents of this page are intended exclusively for healthcare professionals. Where present, the description of the products is for informational purposes only and is not intended for promotion of the same.

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